Anaemia

CHAPTER ONE

1.0     Introduction

1.1     Anaemia

1.1.1  Biochemistry

1.2     Iron therapy

1.3     Biosynthesis of Heme

CHAPTER TWO

2.0     Classification

2.1     Hyporegenerative

2.1.1  Aplastic

2.1.2  Pure red cell aplasia (PRCA)

2.1.3 related to the myelodysplastic syndrome

2.1.4  Deficiency

2.1.5  Bone marrow infiltration and fibrosis

2.1.6  chronic disease (ACD)

2.1.7  chronic renal failure

2.2     Regenerative

2.2.1  Immune haemolytic

2.2.2  Sickle cell

2.2.3  due to enzymopathies and red cell membrane defects

2.2.4  Haemorrhagic

CHAPTER THREE

3.0     Selected

3.1     Pure red cell aplasia

3.2     B12 deficiency

3.3     Immune haemolytic

3.3.1  Classification

3.3.2  Pathophysiology of immune haemolytic

3.3.3  Diagnosis of haemolytic

3.4     Non-immune haemolytic

3.4.1  Paroxysmal nocturnal haemoglobinuria (PNH)

3.4.2  Microangiopathic disorders

3.4.3  Haemolysis secondary to toxic agents and other causes

CHAPTER FOUR

4.0     Conclusion

References