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CHAPTER ONE

1.0     Introduction

1.1     Atherosclerosis

1.2     Pathogenesis

1.2.1  Atherogenesis

1.2.1.1 Initiation

1.2.1.2 Progression

CHAPTER TWO

2.0     Biochemical basis

2.1     Types of  plaque

2.1.1  Features plaques

2.1.1.1 Lipid-rich core

2.1.1.2 Cell death

2.1.1.3 Calcification

2.1.1.4   Neovascularization and intraplaque hemorrhage

2.1.1.5   Vascular remodeling and luminal stenosis

2.1.1.6 Plaque rupture

2.1.1.7 Nonfatal thrombosis

2.1.1.8   Fatal thrombosis

2.1.1.9 Fibrin and platelets

2.1.1.10 Contribution of bone marrow-derived cells

2.1.2  Immunohistochemistry in plaque

CHAPTER THREE

3.0     Inflammation in

3.1     Inflammation and the initiation

3.2     Inflammation causes various forms of plaque disruption

3.3     Inflammation as a therapeutic target in

3.4     Inflammatory markers as gauges risk

3.5     Itherosclerosis and cardiovascular disease

CHAPTER FOUR

4.0     Physical activity in prevention

CHAPTER FIVE

5.0     Conclusion and recommendation

5.1     Conclusion

5.2     Recommendation

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